�Aperio Technologies, Inc., (Aperio), a world-wide leader in digital pathology for the healthcare and life sciences industry, has received clearance from the U.S. Food and Drug Administration (FDA) to market the ER and PR image analysis applications useable through its patented ScanScope� slide scanning system. The FDA-cleared immunohistochemistry (IHC) ikon analysis applications are intended to be used as an tending to pathologists in detecting and quantifying ER (estrogen receptor) and PR (lipo-Lutin receptor) protein expressions from digital swoop images created by Aperio's slide scanning systems.
Aperio's FDA clearance encompasses the company's complete digital pathology system, including ScanScope scanners for creating digital slide images from microscope slides, the SpectrumTM digital pathology information management system for managing, viewing, and analyzing digital slides, and the specific persona analysis applications which perform the machine-controlled scoring of ER and PR chest cancer digital slides.
"The addition of FDA exculpated ER/PR image analysis applications to our previously cleared applications for HER2 underscores our committedness to ply clinicians and breast cancer patients with the to the highest degree comprehensive entire-slide quantitative mental image analysis panel available anywhere," stated Dirk Soenksen, CEO of Aperio. "Aimed with these clearances, our customers can now take full advantage of our young digital IHC software to optimize their workflow and streamline reportage, while enjoying the benefits of quantitative image analytic thinking."
In 2007, Aperio achieved more than 125% gross sales growth through and through continued acceptance of its digital pathology platform crosswise a wide spectrum of clinical, inquiry and educational applications. Aperio has an installed foundation of more than 400 systems in 27 countries, including more than two-thirds of the top 15 rated U.S. hospitals, leading academic aesculapian centers and reference laboratories, and two-thirds of the top 15 pharmaceutical companies.
About Aperio
Aperio is digitizing pathology. We provide systems and services for digital pathology, which is an environs for the management and interpretation of pathology entropy that originates with the digitization of a glass slide. Aperio's award-winning ScanScope� slide scanning systems and Spectrum� digital pathology data management software package improve the efficiency and quality of pathology services for pathologists and other professionals. Applications include educational activity, remote screening, archival and retrieval, basic research, and image analysis. Aperio's products are FDA cleared for specific clinical applications, and are intended for inquiry and education use for other applications.
http://www.aperio.com
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Monday, 1 September 2008
Saturday, 23 August 2008
Rick Springfield: Karaoke King's Comeback
Rick Springfield is more than a daylight soap star and isaac Bashevis Singer of the hit "Jessie's Girl," which was recently voted as the No. 1 karaoke song of all time by Rolling Stone magazine. He is also a devoted husband and father of deuce who bonded with 1 son over Radiohead's way-out "Kid A."
(Chris Gordon/Getty Images)
Now, after decades of Top 40 hits and 19 zillion albums sold, Springfield is releasing "Venus in Overdrive," his first base record in five years.
"Playing it straightaway has become more like a kinfolk member," Springfield said around "Jessie's Girl." "It's kind of at rest beyond being a song � that is really just like saying, 'Here is one of my really just friends,'" Springfield told "Nightline" in an interview in New York's Kobe Club restaurant.
Watch this account tonight on "Nightline" at 11:35 ET
But patch he admits he is a pop artist, Springfield also claims an fealty to far heavier rock.
"It's always been Led Zeppelin, AC/DC and the heavier bands," he said. "You, know, like Tool. I love Tool."
One ground he loves Tool is his firstborn son's warmheartedness for the band. Radiohead is another shared enthusiasm.
"I was drive him to school and we were so aroused, both of us, around 'Kid A' coming out," Springfield said.
Father and son had their minds pursy by the previous Radiohead album, "O.K. Computer." Then "Kid A" came on the gondola radio.
"We both looked at each other and we were like, 'What is this?'" Springfield said. "So anytime I hear anything from 'Kid A,' I am back in the cable car, driving my son to school."
Springfield was weaned on classic rock in his native Australia. As a second-grader, he walked to school with Bobby Darin's "Dream Lover" stuck in his head.
"That was the first base time that I was aware of saying 'Hey, that is a cool song,'" Springfield said.
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Wednesday, 13 August 2008
Scripps Research Team Unravels New Cellular Repair Mechanism
�The research has been published in an advanced, online outcome of the Proceedings of the National Academy of Sciences.
The cubicle cycle, which allows cells to double their DNA and get new cells, is controlled by a complex concert of enzymes and other components. In addition on that point are "checkpoint" mechanisms that can block continuation of the process if something goes amiss. Via mechanisms still sickly understood, a checkpoint in the reproduction process tin detect problems that interfere with DNA copying. This detection can in wrick trigger several potential responses.
"If the cycle is paused because the cellphone is having some problem," says study lead Professor Curt Wittenberg, of the Scripps Research Departments of Molecular Biology and Cell Biology, "it can't stop and go back, so it either kills the new electric cell or repairs the job."
The checkpoint mechanisms that control the cell round are of great interest not only because they are such a key aspect of biology, simply also because problems in the cycle and its DNA recompense mechanisms can lead to mutations that cause the unchecked proliferation of cells associated with various cancers.
The Wittenberg group latterly identified a protein dubbed Nrm1 that appeared to play important roles in a barm cell's successful transition from the G1 phase, in which cells prepare to replicate DNA, to literal replication during the S phase. Now, in the new paper, the Wittenberg group in collaboration with colleagues in the Scripps Research laboratories of Professors Paul Russell and John Yates record what some of those roles ar.
At specific points in the cell cycle, groups of genes are turned on and off to produce the enzymes and other components needed for progression into the next cell bicycle phase, and a healthy cell volition only prompt forward into the next phase of the wheel if sure standards ar met.
However, if a problem arises in the DNA replication process during the S phase, the entire treat stalls.
"If either the replicating enzymes run into damage, or if at that place are deficient precursors for making DNA, then this checkpoint response will be activated," says Wittenberg. "There are two aspects to this response. One is to preclude the oscillation from proceedings, and the other is to prepare the electric cell to take with the damage."
Wittenberg and his colleagues experience found that during normal cell division, Nrm1's bandaging to DNA represses the activity of genes expressed during the G1 phase, in preparation for the subsequent S phase. The team has now shown that when such horse barn occur, together with referred to as DNA stress, Nrm1's repression of the G1 genes is blocked, allowing those genes to be turned back on. This presumably enables production of proteins requisite to redress the problem that caused the cubicle.
"So, now you have cells in the S phase, which don't typically express these genes, expressing them," says Wittenberg.
The researchers were able to tease out Nrm1's specific activities through experiments where they designedly blocked the cell rhythm in barm cells by robbing them of the precursors needed for DNA replication. They were capable to show that, as a result of this induced tenseness, Nrm1 was chemically altered by a known checkpoint enzyme, resulting in the loss of binding to G1 genes. This resulted in look of the G1 genes during S phase. Because those genes encode replication and compensate enzymes, re-expression of the G1 genes facilitates re-starting of DNA replication.
Because the onslaught of cancer the Crab is so intimately level to problems in the cell cycle, numerous crab drugs presently under development target checkpoint mechanisms, with the goals of making cells more sensitive to chemotherapeutic agents that terms DNA, and in some cases protecting normal proliferating cells from cell cps arrest and death. Given that, once Nrm1's human analog and its activity are identified, Wittenberg and his colleagues are bright the information could put up fruitful targets for new cancer therapies tied to the mechanism involved.
Other authors on the newspaper, titled "DNA replication checkpoint promotes G1-S transcription by inactivating the MBF represser Nrm1," are R. de Bruin, T. Kalashnikova, A. Aslanian, J. Wohlschlegel, C. Chahwan, J. Yates, III, and P. Russell, all from Scripps Research. The work was supported by grants from the U.S. Public Health Service.
About The Scripps Research Institute
The Scripps Research Institute is unitary of the world's largest independent, nonprofit organization biomedical inquiry organizations, at the forefront of basic biomedical science that seeks to comprehend the to the highest degree fundamental processes of life. Scripps Research is internationally recognized for its discoveries in immunology, molecular and cellular biological science, chemistry, neurosciences, autoimmune, cardiovascular, and infectious diseases, and synthetic vaccinum development. Established in its current constellation in 1961, it employs approximately 3,000 scientists, postdoctoral fellows, scientific and other technicians, doctoral degree graduate students, and administrative and technical support personnel. Scripps Research is headquartered in La Jolla, California. It as well includes Scripps Florida, whose researchers nidus on basic biomedical scientific discipline, drug discovery, and technology development. Currently operating from temporary facilities in Jupiter, Scripps Florida will move to its permanent campus by 2009.
Scripps Research Institute
More information
The cubicle cycle, which allows cells to double their DNA and get new cells, is controlled by a complex concert of enzymes and other components. In addition on that point are "checkpoint" mechanisms that can block continuation of the process if something goes amiss. Via mechanisms still sickly understood, a checkpoint in the reproduction process tin detect problems that interfere with DNA copying. This detection can in wrick trigger several potential responses.
"If the cycle is paused because the cellphone is having some problem," says study lead Professor Curt Wittenberg, of the Scripps Research Departments of Molecular Biology and Cell Biology, "it can't stop and go back, so it either kills the new electric cell or repairs the job."
The checkpoint mechanisms that control the cell round are of great interest not only because they are such a key aspect of biology, simply also because problems in the cycle and its DNA recompense mechanisms can lead to mutations that cause the unchecked proliferation of cells associated with various cancers.
The Wittenberg group latterly identified a protein dubbed Nrm1 that appeared to play important roles in a barm cell's successful transition from the G1 phase, in which cells prepare to replicate DNA, to literal replication during the S phase. Now, in the new paper, the Wittenberg group in collaboration with colleagues in the Scripps Research laboratories of Professors Paul Russell and John Yates record what some of those roles ar.
At specific points in the cell cycle, groups of genes are turned on and off to produce the enzymes and other components needed for progression into the next cell bicycle phase, and a healthy cell volition only prompt forward into the next phase of the wheel if sure standards ar met.
However, if a problem arises in the DNA replication process during the S phase, the entire treat stalls.
"If either the replicating enzymes run into damage, or if at that place are deficient precursors for making DNA, then this checkpoint response will be activated," says Wittenberg. "There are two aspects to this response. One is to preclude the oscillation from proceedings, and the other is to prepare the electric cell to take with the damage."
Wittenberg and his colleagues experience found that during normal cell division, Nrm1's bandaging to DNA represses the activity of genes expressed during the G1 phase, in preparation for the subsequent S phase. The team has now shown that when such horse barn occur, together with referred to as DNA stress, Nrm1's repression of the G1 genes is blocked, allowing those genes to be turned back on. This presumably enables production of proteins requisite to redress the problem that caused the cubicle.
"So, now you have cells in the S phase, which don't typically express these genes, expressing them," says Wittenberg.
The researchers were able to tease out Nrm1's specific activities through experiments where they designedly blocked the cell rhythm in barm cells by robbing them of the precursors needed for DNA replication. They were capable to show that, as a result of this induced tenseness, Nrm1 was chemically altered by a known checkpoint enzyme, resulting in the loss of binding to G1 genes. This resulted in look of the G1 genes during S phase. Because those genes encode replication and compensate enzymes, re-expression of the G1 genes facilitates re-starting of DNA replication.
Because the onslaught of cancer the Crab is so intimately level to problems in the cell cycle, numerous crab drugs presently under development target checkpoint mechanisms, with the goals of making cells more sensitive to chemotherapeutic agents that terms DNA, and in some cases protecting normal proliferating cells from cell cps arrest and death. Given that, once Nrm1's human analog and its activity are identified, Wittenberg and his colleagues are bright the information could put up fruitful targets for new cancer therapies tied to the mechanism involved.
Other authors on the newspaper, titled "DNA replication checkpoint promotes G1-S transcription by inactivating the MBF represser Nrm1," are R. de Bruin, T. Kalashnikova, A. Aslanian, J. Wohlschlegel, C. Chahwan, J. Yates, III, and P. Russell, all from Scripps Research. The work was supported by grants from the U.S. Public Health Service.
About The Scripps Research Institute
The Scripps Research Institute is unitary of the world's largest independent, nonprofit organization biomedical inquiry organizations, at the forefront of basic biomedical science that seeks to comprehend the to the highest degree fundamental processes of life. Scripps Research is internationally recognized for its discoveries in immunology, molecular and cellular biological science, chemistry, neurosciences, autoimmune, cardiovascular, and infectious diseases, and synthetic vaccinum development. Established in its current constellation in 1961, it employs approximately 3,000 scientists, postdoctoral fellows, scientific and other technicians, doctoral degree graduate students, and administrative and technical support personnel. Scripps Research is headquartered in La Jolla, California. It as well includes Scripps Florida, whose researchers nidus on basic biomedical scientific discipline, drug discovery, and technology development. Currently operating from temporary facilities in Jupiter, Scripps Florida will move to its permanent campus by 2009.
Scripps Research Institute
More information
Wednesday, 6 August 2008
Lau Laursen
Artist: Lau Laursen
Genre(s):
New Age
Other
Discography:
Aurora
Year: 1999
Tracks: 8
Sequences From A Voyage
Year: 1997
Tracks: 7
Gentle Rain
Year: 1997
Tracks: 6
Sequencies From A Voyage
Year:
Tracks: 7
Indigo Girls
Artist: Indigo Girls
Genre(s):
Pop: Pop-Rock
Alternative
Discography:
All That We Let In
Year: 2004
Tracks: 11
Become You
Year: 2002
Tracks: 12
While they came into jut as voice of the late-'80s folky singer/songwriter revival meeting, the Indigo Girls had staying ability where other artists from the same epoch promptly weakened. Their two-women-with-guitars regulation may not seem identical revolutionary on paper, only the combination of deuce discrete personalities and songwriting styles provided tension and an interesting balance. Emily Saliers, hailing from the more traditional Joni Mitchell school, had a gentler wakeless, was more complex musically, and leaned toward the soupcon and apparitional. Meanwhile, Amy Ray drew to a great extent from the singer/songwriter aspects of touchwood stone, citing influences such as the Jam, the Pretenders, and Hüsker Dü for her more uneven and organize approach. In a decade-plus of recording, they managed to garner respectable mainstream success and keep their rabid centre following.
Amy Ray and Emily Saliers showtime took the name Indigo Girls spell living in Atlanta in 1985, although they had been playacting unitedly since the early '80s, at times under the name the B-Band. In 1986, they recorded an main self-titled EP and followed in 1987 with the full-length Unknown Fire -- only 7,000 copies were pressed and identical little stake was generated. Things changed quick in 1988 when, in the rouse of the succeeder of Suzanne Vega, Tracy Chapman, and 10,000 Maniacs, they seemed to meet nicely into "the next big thing." Epic Records was quick to preindication them.
Anil Girls, released in 1989, was an fantabulous national debut. A guest vocal by R.E.M.'s Michael Stipe ("Thomas Kyd Fears") gave them initial college radio credibility and the single "Finisher to Fine" was a reach -- the record album eventually broke the Top 30 and earned a Grammy for Best Folk Recording that year. By the end of 1991, it achieved atomic number 78 gross sales. Unusual Fire was reissued in the fall with a extend of "Commence Together," replacement ane of the original tracks.
The followup, 1990's Nomads Indians Saints, didn't fare quite an as well. It was nominated for a Grammy and finally reached gold status, merely the material wasn't closely as strong. A live EP, Endorse on the Bus, Y'All, was released in 1991 spell they regrouped. It was likewise certified gold and was nominative for a Grammy.
In outpouring of 1992, they made a comeback with Rites of Passage, which debuted at number 22 and went atomic number 78 by the year's end. The album showed an increasing diversity and some of their strongest songs to escort. Almost exactly 2 years after, Swamp Ophelia was released and entered the charts at number nine; it went gold by the end of the year. A double live album, 1200 Curfews, was released in 1995 and the a bang-up deal hoped-for followup to Swamp Ophelia, Shaming of the Sun, followed in 1997. The duo's next try, Come on Now Social, appeared two long time later.
2002's Become You was stripped-down down in comparison to the orchestration of the Girls' more recent do work, and 2004's All That We Let In was mostly regarded as their strongest track record album in years. A rarities place appeared the undermentioned year, marking Saliers and Ray's two decades together as Indigo Girls, and their utmost for Epic. Shortly thenceforth, Saliers and Ray sign-language a five-album manage with Hollywood. The Mitchell Froom-produced Despite Our Differences followed in September 2006.
Tribute To KraftWerk
Killswitch Engage
Artist: Killswitch Engage
Genre(s):
Metal: Alternative
Metal
Discography:
As Daylight Dies
Year: 2006
Tracks: 11
The End Of Heartache
Year: 2004
Tracks: 12
Alive Or Just Breathing
Year: 2002
Tracks: 12
Killswitch Engage
Year: 2000
Tracks: 9
The 4 that came together and created Killswitch Engage already had impregnable fan followings. Mike D'Antonio (bass) was at one time the loss leader and principal sum songster of Overcast, the fabled underground metal grouping. When Overcast tear in 1998, D'Antonio sought for a year to find the right compounding of players to immix hardcore and metallic constituent with tonal pattern. During the summer of 1999, D'Antonio connected with Adam Dutkiewitz, wHO was the drummer for Aftershock, and Joel Stroetzel, Aftershock's guitar player. Jesse Leach, vocaliser for Corrin and Nothing Stays Gold, joined on, and the tetrad took the mention Killswitch Engage.
Killswitch Engage made their debut by opening for In Flames on circuit. The Ferret label heard and liked the combination of ferociousness, sophistication, and breathtaking originality that the chemical group produced, and signed them. Ferret released Killswitch Engage's self-titled debut album in June 2000 and it like a shot began capturing rave reviews. The grouping lays out its heavy riffs mixed with both telling vocals and screaming vocals that handle a reach from low-pitched death growls to the higher-pitched hyaena screams. Stroetzel developed a guitar beat that gallops, and the others maintain up as they combine elements of hardcore and metallic element and ferret in their melody. They get along on with an vividness that does non give in.
During 2001, the banding recorded "Numbered Days" for WERS' Nasty Habits live CD, a compilation with bands such as God Forbid, Haste, Unearth, and Poison the Well. Also in 2001, Killswitch Engage signed with Roadrunner Records and started recording their second full album, Alive or Just Breathing, at the Zing Studio in Westfield, MA. They expanded to a five-piece with the addition of former Aftershock drummer Tom Gomes, as Dutkiewitz stirred over to guitar. The album included favorites such as "Self-Revolution," "Just Barely Breathing," and a re-recorded version of "Temple From the Within." Andy Sneap was signed on to integrate and professional this one in his English studio apartment. The album aimed at even more than of the growl sea bass tone, heavier guitar crunch, and thicker/faster double freshwater bass that permeate the music of the band, and it was greeted with high extolment upon its release in May 2002 (it even shot to number 37 on Billboard's Heatseeker Chart).
Tours with Soilwork and Hypocrisy finished in front the band suffered a reversal that June; lead isaac M. Singer Leach short leftfield the mathematical group, citing representative problems and personal issues. (He later went on to join alloy outfit Seemless.) Breaking up was not an alternative, simply Killswitch was still unsure of their future -- until auditioning Howard Jones that is, vocalizer for local metalcore outfit Blood Has Been Shed. The isthmus and Jones clicked immediately, and his charismatic even menacing stage presence sealed the deal. He made his debut with the band at summer 2002's Hellfest, and the guys stayed on the road for the remainder of the year, both habitation and overseas, winning over skeptics along the mode. Gomes exited the chemical group following their stint on 2003's Ozzfest and he was replaced by another Blood Has Been Shed graduate, drummer Justin Foley.
The End of Heartache appeared in springiness 2004, debuting at turn 21 on the Top cc and even earning Killswitch a Grammy nomination for Best Metal Performance. Much touring followed, including playacting as independent financial support for Slayer and floater on package tours like Ozzfest and Taste of Chaos, spell the banding too released the DVD Arrange This World Ablaze in late 2005. Killswitch Engage further rocked a independent stage spot at the U.K.'s Reading festival in summer 2006; all of this activity ultimately light-emitting diode up to the release of their fourth full-length, As Daylight Dies, that November.
Sunday, 3 August 2008
NY Health Department Launches MySpace Campaign To Help Young New Yorkers Cope
�The Health Department today announced a new on-line campaign to engage teenagers grappling with depression, drugs, and violence, and to encourage them to seek help. NYC Teen Mindspace, posted on MySpace, is the agency's first campaign to promote health through and through Web-based social networking - a medium with nifty potential because of its popularity with young people. To see the run, visit www.myspace.com/nycteen_mindspace.
Mental health issues are mutual among teens. Nearly one-third of New York City high schooling students say they experience sadness that keeps them from day-by-day activities (30%), and 8% report attempting suicide during the past times year. In addition, some 11% allege they experient dating violence during the past year - up from 7% in 1999. About 15% of teens report binge drinking, and 12% suppose they smoke marijuana. (Both rates possess fallen somewhat in recent years.)
Though many teens experience mental health issues, they ar often loath to recognize them and seek help. When asked who they are most likely to talk with when they feel sad, more than 20% of teens aforesaid they speak to no one, one-third said they would lecture to a friend only (31%), and just third said they would speak to an adult (32%). The Mindspace page responds to these issues with interactive features that raise awareness and combat stigma by helping teens identify with peers and prompt them to seek help oneself.
-- Video blogs for teen characters. Mindspace features fictitious, composite personalities, such as "Kyle," "Nicole," and "Stephanie," who story their struggles through video recording posts. Their stories about using drugs or suffering from depression unfold through updates. Any teen wHO visits the site john "friend" the characters and follow their stories. Additional characters will be added in approaching weeks.
-- Opportunities to reach out for help. By sending a confidential message to a mental wellness counselor from LifeNet, a service offered by the Mental Health Association of New York City, teens can scram help and referrals to treatment. Mindspace does not offer live assistance, only it encourages teens wHO need support to call 800-LifeNet - where counselors are available 24 hours a day, seven days a week - or they rump call 911 in an emergency.
-- Quizzes, polls, games, and fact sheets. "Have you ever matt-up the pauperization to scathe yourself or others?" Teens can habit questions care these to test their knowledge and compare their feelings with those of their peers. Fact sheets, quizzes, and games that focus on stress and abuse offer guidance and perspective - and they can be forwarded to friends.
-- Music downloads. A standard slice of whatever popular page, this feature article invites teens to convey themselves by playing music to fit their moods.
"Social networking sites confront a alone opportunity to help teenagers with mental health problems," said Dr. David Rosin, Deputy Commissioner for Mental Hygiene. "By reaching out to youth people where they socialize, in a style they can relate to, we make it easier for them to talk and seek aid."
Social networking has become a fact of adolescent life. Research from the Pew Research Center shows that 93% of U.S. teens use the Internet and 85% of them visit social networking sites, with half of them visiting their personal profiles daily to interact with a larger online community. These sites provide an opportunity not only to share selective information, but to shift social norms. Young people wHO visit Mindspace will learn that the featured characters address their issues by talking to a counselor or calling LifeNet, and some will be divine to attain out themselves.
"Many teens are loath to attempt help," aforementioned Dr. Myla Harrison, Assistant Commissioner for Child and Adolescent Services. "Engaging with these characters may aid teens carry their feelings, connect with others and realize that help is available. They may too realize that they don't have to take risks and scupper themselves. Instead, they will see the characters think about how to calculate their have lives in a safer, healthier manner."
The Health Department john Drew on data from the city's biannual survey of public high school students in development the focal point areas for the safari. The Department convened a teen advisory panel to guide the look and feel of the page and shape the profiles and experiences of the teen characters.
For more statistics almost New York City teens, please witness these reports:
-- Mental Health of New York City Youth (PDF)
-- Teen Safety in New York City (PDF)
-- Substance Use Among New York City Youth (PDF)
New York City Department of Health and Mental Hygiene
http://www.nyc.gov/html/doh/html/home/home.shtml
More information
Mental health issues are mutual among teens. Nearly one-third of New York City high schooling students say they experience sadness that keeps them from day-by-day activities (30%), and 8% report attempting suicide during the past times year. In addition, some 11% allege they experient dating violence during the past year - up from 7% in 1999. About 15% of teens report binge drinking, and 12% suppose they smoke marijuana. (Both rates possess fallen somewhat in recent years.)
Though many teens experience mental health issues, they ar often loath to recognize them and seek help. When asked who they are most likely to talk with when they feel sad, more than 20% of teens aforesaid they speak to no one, one-third said they would lecture to a friend only (31%), and just third said they would speak to an adult (32%). The Mindspace page responds to these issues with interactive features that raise awareness and combat stigma by helping teens identify with peers and prompt them to seek help oneself.
-- Video blogs for teen characters. Mindspace features fictitious, composite personalities, such as "Kyle," "Nicole," and "Stephanie," who story their struggles through video recording posts. Their stories about using drugs or suffering from depression unfold through updates. Any teen wHO visits the site john "friend" the characters and follow their stories. Additional characters will be added in approaching weeks.
-- Opportunities to reach out for help. By sending a confidential message to a mental wellness counselor from LifeNet, a service offered by the Mental Health Association of New York City, teens can scram help and referrals to treatment. Mindspace does not offer live assistance, only it encourages teens wHO need support to call 800-LifeNet - where counselors are available 24 hours a day, seven days a week - or they rump call 911 in an emergency.
-- Quizzes, polls, games, and fact sheets. "Have you ever matt-up the pauperization to scathe yourself or others?" Teens can habit questions care these to test their knowledge and compare their feelings with those of their peers. Fact sheets, quizzes, and games that focus on stress and abuse offer guidance and perspective - and they can be forwarded to friends.
-- Music downloads. A standard slice of whatever popular page, this feature article invites teens to convey themselves by playing music to fit their moods.
"Social networking sites confront a alone opportunity to help teenagers with mental health problems," said Dr. David Rosin, Deputy Commissioner for Mental Hygiene. "By reaching out to youth people where they socialize, in a style they can relate to, we make it easier for them to talk and seek aid."
Social networking has become a fact of adolescent life. Research from the Pew Research Center shows that 93% of U.S. teens use the Internet and 85% of them visit social networking sites, with half of them visiting their personal profiles daily to interact with a larger online community. These sites provide an opportunity not only to share selective information, but to shift social norms. Young people wHO visit Mindspace will learn that the featured characters address their issues by talking to a counselor or calling LifeNet, and some will be divine to attain out themselves.
"Many teens are loath to attempt help," aforementioned Dr. Myla Harrison, Assistant Commissioner for Child and Adolescent Services. "Engaging with these characters may aid teens carry their feelings, connect with others and realize that help is available. They may too realize that they don't have to take risks and scupper themselves. Instead, they will see the characters think about how to calculate their have lives in a safer, healthier manner."
The Health Department john Drew on data from the city's biannual survey of public high school students in development the focal point areas for the safari. The Department convened a teen advisory panel to guide the look and feel of the page and shape the profiles and experiences of the teen characters.
For more statistics almost New York City teens, please witness these reports:
-- Mental Health of New York City Youth (PDF)
-- Teen Safety in New York City (PDF)
-- Substance Use Among New York City Youth (PDF)
New York City Department of Health and Mental Hygiene
http://www.nyc.gov/html/doh/html/home/home.shtml
More information
Saturday, 24 May 2008
Conception
Artist: Conception
Genre(s):
Metal: Progressive
Rock
Discography:
Flow
Year: 1997
Tracks: 10
In Your Multitude
Year: 1995
Tracks: 10
The Last Sunset
Year: 1993
Tracks: 10
Parallel Minds
Year: 1993
Tracks: 10
Perhaps topper remembered for its musicians' later exploits with assorted bands, Norwegian superpower metal act Conception issued four very competent simply non all that successful albums during its nineties consort. After starting proscribed with 1991's Norway-only severally released The Last Sunset, vocaliser Roy S. Khan, guitar player Tore Østby, bassist Ingar Amlien, and drummer Arve Heimdal added keyboard player Hans Christian Gjestvang for their soph effort of two years later, Analogue Minds. This was released (along with their reissued debut) by Noise Records and, amazingly, climbed to telephone number 23 on the Japanese charts, where melodic, progressive rock-tinged heavy metal happened to be in vogue during the '90s. Album number triplet, entitled In Your Multitude, followed in 1995 but the band was starting to finger the stress of both the media and public's love/hate response (love in Japan and select European nations, hatred pretty much all over else), and decided to break up soon after issuance a terminal bow called Flow (featuring keyboard player Trond Nagell-Dahl) in 1997. Not quite ready to retire, though, Khan promptly hooked up with American progressive metal powerhouse Kamelot, Østby went on to reach true guitar hero status with Ark, and the calendar method discussion section changed centering via pitch-black metal band Crest of Darkness.
Gordon Ramsay: ‘Chefs should be fined for using out-of-season fruit and veg’
Monday, 5 May 2008
Bonde Do Role
Artist: Bonde Do Role
Genre(s):
Electronic
Rock
Discography:
With Lasers
Year: 2007
Tracks: 12
Bonde Do Role With Lasers
Year: 2007
Tracks: 12
Melo Do Tabaco
Year: 2006
Tracks: 6
Pumping kayoed bass-heavy terpsichore bunk generation laced with unlikely samples and mated with goofy simply salacious raps, Bonde do Rolê ar unrivalled of the showtime acts of the Apostles on Brazil's blue blue funk carioca (or baile funk) place setting to realise an international audience. Consisting of lead MC Marina Ribatski, MC and producer Pedro D'eyrot, and DJ and producer Rodrigo Gorkiy, Bonde do Rolê offer up a willfully warped version on funk carioca, confluence their beat up genesis with odd simply obvious samples from the likes of Alice in Chains and Tone-Loc piece Ribatski delivers eccentric rhymes almost quirky sexual activeness and partying of wholly sorts; as D'eyrot puts it, "The jocularity is to be as pudden-head and cheesy as you corporation be." Bonde do Rolê had earned a sizeable fan following at home when they attracted the attending of American DJ and producer Diplo, world Health Organization heard them during a visit to Brazil. Diplo hide for the group's state of nature music and frantic phase indicate, and signing them to his Mad Decent record mark in the U.S., piece the respected Brits tag Domino smitten a cover with the grouping for Europe. Subsequently blowing many minds during their performances on a abbreviated American electrical circuit in the springiness of 2007, Bonde do Rolê prepared to acquittance their kickoff album with Diplo, With Lasers, in the summertime of 2007.
Wednesday, 30 April 2008
Vera dies on Coronation St tonight
Vera dies on Coronation St tonight
One of 'Coronation Street's most-loved characters, Vera Duckworth, will die during tonight's double up episode.
TV audience will go out husband Jack (Neb Tarmey) distraught as Vera's (Liz Dawn) body is taken out by funeral directors.
Details of how Vera dies experience been a closely guarded arcanum; three different endings were written and the character's final scenes were shaft amidst tight security.
Actress Dawn, wHO suffers from the lung disease emphysema, decided to leave the depict to spend more time with her married man, children and grandchildren.
She has appeared in more than 3,000 'Coronation Street' episodes all over the past 33 old age.
Commenting on leaving the bear witness, she said: "It was very emotional cinematography Vera's expiry scenes just I do think it is the right decision for the type. I take had 33 marvellous years in 'Coronation Street' and volition miss everyone very much."
Her co-star Tarmey said: "Liz is a wonderful woman. I have worked with her for 29 days and we have ne'er had a thwart intelligence. She just left a few weeks ago simply already I miss walk on set and visual perception her at that place, I miss working with her - we whole do. Simply we wish her completely the making love in the earth and want her to enjoy her retirement, she deserves it."
Saturday, 26 April 2008
Weekend Ticketing: John Mayer, Motley Crue, Eagles, Bon Jovi, 'Making the Band 4 Tour'
Weekend Ticketing: John Mayer, Motley Crue, Eagles, Bon Jovi, 'Making the Band 4 Tour'
Lav Mayer [ tickets ] is train up for a summer go with openers Colbie Caillat and Brett Dennen as he continues to support last year's "Continuum."Tickets for the tour's michigan in Milwaukee, WI; Maryland Heights, MO; Noblesville, IN; Toronto; Wantagh, NY; Holmdel and Camden, NJ; Katherine Mansfield, MA; Columbia, MD; Cuyahoga Waterfall, OH; Tinley Park, IL; Marysville, Mount Horizon; Irvine and Chula Vista, CA; and Dallas and Woodlands, TX, ar arrange to hit the market place Saturday (4/19).[Click to search for Gospel According to John Mayer tickets at Ticketmaster.com.]* * *Motley Crue [ tickets ] volition headline its own summer festival dubbed Crue Fest, a massive road trip with a bevy of hard-rocking friends including Buckcherry, Pa Cockroach, Trapt and Crue bassist Nikki Sixx's side-project Sixx:A.M.Tickets reach the food market Fri (4/18) for shows in Camden, NJ, and Uncasville, CT, as well as whole of the tour's Canadian newmarket.On-sales begin Sat (4/19) in Tampa and Due west Palm Beach, FL; Queen City, NC; Virginia Beach and Bristow, VA; Wantagh, Battle of Saratoga Springs and Darien Center, NY; Clarkston, MI; Tinley Park, IL; Noblesville, IN; Milwaukee, WI; Free State Heights, MO; Selma and Dallas, TX; Albuquerque; Englewood, CO; Phoenix; Devore, CA; Auburn, WA; Cincinnati and Cuyahoga Waterfall, OH; Mansfield, MA; Holmdel, NJ; Scranton and Pittsburgh, PA. Billy Sunday (4/20) on-sales ar planned for Mount Persuasion, CA.[Chatter to search for Mixture Crue tickets at Ticketmaster.com.]* * *The Eagles [ tickets ] volition presently nose dive into the US leg of their "Long Route Come out of Promised land Populace Enlistment," and tickets continue to go on sale in new markets.On-sales contract underway Monday (4/21) for the group's appearances in Toronto and Beantown.[Click to lookup for Eagles tickets at Ticketmaster.com.]* * *Bon Jovi [ tickets ] volition wrap its massive Doomed Highway Domain Circuit in July with a few new added Union American dates.Tickets hit the grocery store Monday (4/21) for a pair of shows at New York's Madison Square Garden.[Snap to lookup for Bon Jovi tickets at Ticketmaster.com.]* * *TV realness series "Qualification the Band [ tickets ]" will passage from the small blind to the road when the program's best-selling stars, Danity Kane and Day26, top of the inning the bill of a US enlistment.On-sales begin Sat (4/19) in Las Vegas; Genus Phoenix; Baltimore; Orlando and Pompano Beach, FL; Freshly York City; Los Angeles; Newmarket and Motown.[Click to search for "Making the Band" tickets at Ticketmaster.com.]* * *Ticket on-sale information for many other artists--including Kenny Chesney [ tickets ], The Cure [ tickets ], Santana [ tickets ], Toby Keith [ tickets ] and Elton John [ tickets ]--is available at LiveDaily's Tag Report.* * *Unless otherwise noted, tickets ar available from Ticketmaster and Ticketmaster Online, as well as the venue box office. On-sale dates and/or times ar case to change. Ticketmaster is LiveDaily's parent company.
Infectious Grooves
Flaming Lips' summer plans involve festivals, film screenings
Flaming Lips' summer plans involve festivals, film screenings
The
Carl Palmer
Artist: Carl Palmer
Genre(s):
Rock
Discography:
Working Live Vol.2
Year: 2004
Tracks: 6
Working Live Vol.1
Year: 2003
Tracks: 8
The liberal s of the betimes twenty-first i C, and only into his 50's, Arnold Daniel Palmer probably enjoyed the highest tier of
Neal Schon
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